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The adenovirus priming protein pTP contributes to the kinetics of initiation of DNA replication

Adenovirus (Ad) precursor terminal protein (pTP) in a complex with Ad DNA polymerase (pol) serves as a primer for Ad DNA replication. During initiation, pol covalently couples the first dCTP with Ser-580 of pTP. By using an in vitro reconstituted replication system comprised of purified proteins, we...

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Detalhes bibliográficos
Main Authors: Mysiak, Monika E., Holthuizen, P. Elly, van der Vliet, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC506811/
https://ncbi.nlm.nih.gov/pubmed/15273278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh726
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