Sequence-specific artificial ribonucleases. I. Bis-imidazole-containing oligonucleotide conjugates prepared using precursor-based strategy

Antisense oligonucleotide conjugates, bearing constructs with two imidazole residues, were synthesized using a precursor-based technique employing post-synthetic histamine functionalization of oligonucleotides bearing methoxyoxalamido precursors at the 5′-termini. The conjugates were assessed in ter...

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Hlavní autoři: Beloglazova, Natalia G., Fabani, Martin M., Zenkova, Marina A., Bichenkova, Elena V., Polushin, Nikolai N., Sil'nikov, Vladimir V., Douglas, Kenneth T., Vlassov, Valentin V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC506794/
https://ncbi.nlm.nih.gov/pubmed/15273275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh702
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