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Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase
Rotation of a DNA or RNA nucleotide out of the double helix and into a protein pocket (‘base flipping’) is a mechanistic feature common to some DNA/RNA-binding proteins. Here, we report the structure of HhaI methyltransferase in complex with DNA containing a south-constrained abasic carbocyclic suga...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC506793/ https://ncbi.nlm.nih.gov/pubmed/15273274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh701 |
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