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The "Goldilocks Effect" in Cystic Fibrosis: identification of a lung phenotype in the cftr knockout and heterozygous mouse

BACKGROUND: Cystic Fibrosis is a pleiotropic disease in humans with primary morbidity and mortality associated with a lung disease phenotype. However, knockout in the mouse of cftr, the gene whose mutant alleles are responsible for cystic fibrosis, has previously failed to produce a readily, quantif...

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Bibliografski detalji
Izdano u:BMC Genet
Glavni autori: Craig Cohen, J, Lundblad, Lennart KA, Bates, Jason HT, Levitzky, Michael, Larson, Janet E
Format: Artigo
Jezik:Inglês
Izdano: BMC 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC506778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15279681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2156-5-21
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