Inhibition of P2X Receptors Protects Human Monocytes against Damage by Leukotoxin from Aggregatibacter actinomycetemcomitans and α-Hemolysin from Escherichia coli

α-Hemolysin (HlyA) from Escherichia coli and leukotoxin A (LtxA) from Aggregatibacter actinomycetemcomitans are important virulence factors in ascending urinary tract infections and aggressive periodontitis, respectively. The extracellular signaling molecule ATP is released immediately after inserti...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Fagerberg, Steen K., Jakobsen, Martin R., Skals, Marianne, Praetorius, Helle A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067745/
https://ncbi.nlm.nih.gov/pubmed/27528275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00674-16
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