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P2X Receptor-Dependent Erythrocyte Damage by α-Hemolysin from Escherichia coli Triggers Phagocytosis by THP-1 Cells
The pore-forming exotoxin α-hemolysin from E. coli causes a significant volume reduction of human erythrocytes that precedes the ultimate swelling and lysis. This shrinkage results from activation of Ca(2+)-sensitive K(+) (K(Ca)3.1) and Cl(−) channels (TMEM16A) and reduced functions of either of the...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705273/ https://ncbi.nlm.nih.gov/pubmed/23462688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins5030472 |
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