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Escherichia coli α-Hemolysin Triggers Shrinkage of Erythrocytes via K(Ca)3.1 and TMEM16A Channels with Subsequent Phosphatidylserine Exposure

α-Hemolysin from Escherichia coli (HlyA) readily lyse erythrocytes from various species. We have recently demonstrated that this pore-forming toxin provokes distinct shrinkage and crenation before it finally leads to swelling and lysis of erythrocytes. The present study documents the underlying mech...

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Detalhes bibliográficos
Main Authors: Skals, Marianne, Jensen, Uffe B., Ousingsawat, Jiraporn, Kunzelmann, Karl, Leipziger, Jens, Praetorius, Helle A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865299/
https://ncbi.nlm.nih.gov/pubmed/20231275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.082578
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