Fluorescent Trimethoprim Conjugate Probes To Assess Drug Accumulation in Wild Type and Mutant Escherichia coli

[Image: see text] Reduced susceptibility to antimicrobials in Gram-negative bacteria may result from multiple resistance mechanisms, including increased efflux pump activity or reduced porin protein expression. Up-regulation of the efflux pump system is closely associated with multidrug resistance (...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Phetsang, Wanida, Pelingon, Ruby, Butler, Mark S., KC, Sanjaya, Pitt, Miranda E., Kaeslin, Geraldine, Cooper, Matthew A., Blaskovich, Mark A. T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067704/
https://ncbi.nlm.nih.gov/pubmed/27737551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00080
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