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Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Fluorescent probes derived from the fluoroquinolone antibiotic ciprofloxacin were synthesised using a Cu(i)-catalysed azide–alkyne cycloaddition (CuAAC) to link a ciprofloxacin azide derivative with alkyne-substituted green and blue fluorophores. The azide (2) and fluorophore (3 and 4) derivatives r...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Stone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A., Blaskovich, Mark A. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596217/
https://ncbi.nlm.nih.gov/pubmed/31303987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00124g
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