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Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8
Microtubule‐associated protein tau becomes abnormally phosphorylated in Alzheimer's disease and other tauopathies and forms aggregates of paired helical filaments (PHF‐tau). AT8 is a PHF‐tau‐specific monoclonal antibody that is a commonly used marker of neuropathology because of its recognition...
Zapisane w:
| Wydane w: | Proteins |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067699/ https://ncbi.nlm.nih.gov/pubmed/26800003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24988 |
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