Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8

Microtubule‐associated protein tau becomes abnormally phosphorylated in Alzheimer's disease and other tauopathies and forms aggregates of paired helical filaments (PHF‐tau). AT8 is a PHF‐tau‐specific monoclonal antibody that is a commonly used marker of neuropathology because of its recognition...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Malia, Thomas J., Teplyakov, Alexey, Ernst, Robin, Wu, Sheng‐Jiun, Lacy, Eilyn R., Liu, Xuesong, Vandermeeren, Marc, Mercken, Marc, Luo, Jinquan, Sweet, Raymond W., Gilliland, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067699/
https://ncbi.nlm.nih.gov/pubmed/26800003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24988
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados