Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8

Microtubule‐associated protein tau becomes abnormally phosphorylated in Alzheimer's disease and other tauopathies and forms aggregates of paired helical filaments (PHF‐tau). AT8 is a PHF‐tau‐specific monoclonal antibody that is a commonly used marker of neuropathology because of its recognition...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proteins
Glavni autori: Malia, Thomas J., Teplyakov, Alexey, Ernst, Robin, Wu, Sheng‐Jiun, Lacy, Eilyn R., Liu, Xuesong, Vandermeeren, Marc, Mercken, Marc, Luo, Jinquan, Sweet, Raymond W., Gilliland, Gary L.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067699/
https://ncbi.nlm.nih.gov/pubmed/26800003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24988
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items