Wird geladen...

Protein crystallization with microseed matrix screening: application to human germline antibody Fabs

The crystallization of 16 human antibody Fab fragments constructed from all pairs of four different heavy chains and four different light chains was enabled by employing microseed matrix screening (MMS). In initial screening, diffraction-quality crystals were obtained for only three Fabs, while many...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Obmolova, Galina, Malia, Thomas J., Teplyakov, Alexey, Sweet, Raymond W., Gilliland, Gary L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118815/
https://ncbi.nlm.nih.gov/pubmed/25084393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14012552
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!