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Structural diversity in a human antibody germline library
To support antibody therapeutic development, the crystal structures of a set of 16 germline variants composed of 4 different kappa light chains paired with 4 different heavy chains have been determined. All four heavy chains of the antigen-binding fragments (Fabs) have the same complementarity-deter...
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Izdano u: | MAbs |
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Glavni autori: | , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Taylor & Francis
2016
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968113/ https://ncbi.nlm.nih.gov/pubmed/27210805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1190060 |
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