A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus

BACKGROUND: Exportin 1 (XPO1/CRM1) plays prominent roles in the regulation of nuclear protein export. Selective inhibitors of nuclear export (SINE) are small orally bioavailable molecules that serve as drug‐like inhibitors of XPO1, with potent anti‐cancer properties. Traumatic brain injury (TBI) pre...

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Publicado en:CNS Neurosci Ther
Main Authors: Tajiri, Naoki, De La Peña, Ike, Acosta, Sandra A., Kaneko, Yuji, Tamir, Sharon, Landesman, Yosef, Carlson, Robert, Shacham, Sharon, Borlongan, Cesar V.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067638/
https://ncbi.nlm.nih.gov/pubmed/26842647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12501
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