A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus

BACKGROUND: Exportin 1 (XPO1/CRM1) plays prominent roles in the regulation of nuclear protein export. Selective inhibitors of nuclear export (SINE) are small orally bioavailable molecules that serve as drug‐like inhibitors of XPO1, with potent anti‐cancer properties. Traumatic brain injury (TBI) pre...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Tajiri, Naoki, De La Peña, Ike, Acosta, Sandra A., Kaneko, Yuji, Tamir, Sharon, Landesman, Yosef, Carlson, Robert, Shacham, Sharon, Borlongan, Cesar V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067638/
https://ncbi.nlm.nih.gov/pubmed/26842647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12501
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