A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus

BACKGROUND: Exportin 1 (XPO1/CRM1) plays prominent roles in the regulation of nuclear protein export. Selective inhibitors of nuclear export (SINE) are small orally bioavailable molecules that serve as drug‐like inhibitors of XPO1, with potent anti‐cancer properties. Traumatic brain injury (TBI) pre...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Tajiri, Naoki, De La Peña, Ike, Acosta, Sandra A., Kaneko, Yuji, Tamir, Sharon, Landesman, Yosef, Carlson, Robert, Shacham, Sharon, Borlongan, Cesar V.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067638/
https://ncbi.nlm.nih.gov/pubmed/26842647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12501
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