Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

AIMS: The mitochondria are important sources of reactive oxygen species (ROS) in the heart. Mitochondrial ROS production has been implicated in the pathogenesis of diabetic cardiomyopathy, suggesting that therapeutic strategies specifically targeting mitochondrial ROS may have benefit in this diseas...

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Udgivet i:Free Radic Biol Med
Main Authors: Ni, Rui, Cao, Ting, Xiong, Sidong, Ma, Jian, Fan, Guo-Chang, Lacefield, James C., Lu, Yanrong, Le Tissier, Sydney, Peng, Tianqing
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066872/
https://ncbi.nlm.nih.gov/pubmed/26577173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.11.013
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