Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

AIMS: The mitochondria are important sources of reactive oxygen species (ROS) in the heart. Mitochondrial ROS production has been implicated in the pathogenesis of diabetic cardiomyopathy, suggesting that therapeutic strategies specifically targeting mitochondrial ROS may have benefit in this diseas...

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Publicat a:Free Radic Biol Med
Autors principals: Ni, Rui, Cao, Ting, Xiong, Sidong, Ma, Jian, Fan, Guo-Chang, Lacefield, James C., Lu, Yanrong, Le Tissier, Sydney, Peng, Tianqing
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066872/
https://ncbi.nlm.nih.gov/pubmed/26577173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.11.013
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