Therapeutic inhibition of mitochondrial reactive oxygen species with mito-TEMPO reduces diabetic cardiomyopathy

AIMS: The mitochondria are important sources of reactive oxygen species (ROS) in the heart. Mitochondrial ROS production has been implicated in the pathogenesis of diabetic cardiomyopathy, suggesting that therapeutic strategies specifically targeting mitochondrial ROS may have benefit in this diseas...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Ni, Rui, Cao, Ting, Xiong, Sidong, Ma, Jian, Fan, Guo-Chang, Lacefield, James C., Lu, Yanrong, Le Tissier, Sydney, Peng, Tianqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066872/
https://ncbi.nlm.nih.gov/pubmed/26577173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.11.013
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