Identification of Novel S-Nitrosation Sites in Soluble Guanyl Cyclase, the Nitric Oxide Receptor

Soluble Guanylyl Cyclase (sGC) is the main receptor for nitric oxide (NO). NO activates sGC to synthesize cGMP, triggering a plethora of signals. Recently, we discovered that NO covalently modifies select sGC cysteines via a post-translational modification termed S-nitrosation or S-nitrosylation. Ea...

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Udgivet i:J Proteomics
Main Authors: Beuve, Annie, Wu, Changgong, Cui, Chuanlong, Liu, Tong, Jain, Mohit Raja, Huang, Can, Yan, Lin, Kholodovych, Vladyslav, Li, Hong
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066868/
https://ncbi.nlm.nih.gov/pubmed/26917471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2016.02.009
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