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Synergistic effects of A-B-C-type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma

P-glycoprotein (P-gp) overexpression has become the most common cause of occurrence of multidrug resistance in clinical settings. We aimed to construct a micellar polymer carrier to sensitize drug-resistant tumors to doxorubicin (DOX). This A-B-C-type amphiphilic copolymer was prepared by the sequen...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhang, Lu, Lu, Jiafei, Qiu, Liyan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066852/
https://ncbi.nlm.nih.gov/pubmed/27785023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S115956
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