The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance In Vitro and In Vivo Derived from Human Breast MCF-7/ADR Cells

PURPOSE: P-glycoprotein mediated efflux is one of the main mechanisms for multidrug resistance in cancers, and 3-Bromopyruvate acts as a promising multidrug resistance reversal compound in our study. To test the ability of 3-Bromopyruvate to overcome P-glycoprotein-mediated multidrug resistance and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Long, Xu, Jun, Yuan, Weiqi, Wu, Baojian, Wang, Hao, Liu, Guangquan, Wang, Xiaoxiong, Du, Jun, Cai, Shaohui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221289/
https://ncbi.nlm.nih.gov/pubmed/25372840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112132
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