Knockdown of SALL4 inhibits the proliferation and reverses the resistance of MCF-7/ADR cells to doxorubicin hydrochloride

BACKGROUND: Breast cancer is the most frequent malignancy in women and drug resistance is the major obstacle for its successful chemotherapy. In the present study, we analyzed the involvement of an oncofetal gene, sal-like 4 (SALL4), in the tumor proliferation and drug resistance of human breast can...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Chen, Yuan-Yuan, Li, Zhi-Zhen, Ye, Yuan-Yuan, Xu, Feng, Niu, Rui-Jie, Zhang, Hong-Chen, Zhang, Yi-Jian, Liu, Ying-Bin, Han, Bao-San
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776391/
https://ncbi.nlm.nih.gov/pubmed/26935744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0055-y
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