Knockdown of SALL4 inhibits the proliferation and reverses the resistance of MCF-7/ADR cells to doxorubicin hydrochloride

BACKGROUND: Breast cancer is the most frequent malignancy in women and drug resistance is the major obstacle for its successful chemotherapy. In the present study, we analyzed the involvement of an oncofetal gene, sal-like 4 (SALL4), in the tumor proliferation and drug resistance of human breast can...

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Опубликовано в: :BMC Mol Biol
Главные авторы: Chen, Yuan-Yuan, Li, Zhi-Zhen, Ye, Yuan-Yuan, Xu, Feng, Niu, Rui-Jie, Zhang, Hong-Chen, Zhang, Yi-Jian, Liu, Ying-Bin, Han, Bao-San
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776391/
https://ncbi.nlm.nih.gov/pubmed/26935744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0055-y
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