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Identification and molecular characterization of cellular factors required for glucocorticoid receptor-mediated mRNA decay
Glucocorticoid (GC) receptor (GR) has been shown recently to bind a subset of mRNAs and elicit rapid mRNA degradation. However, the molecular details of GR-mediated mRNA decay (GMD) remain unclear. Here, we demonstrate that GMD triggers rapid degradation of target mRNAs in a translation-independent...
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| Udgivet i: | Genes Dev |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5066615/ https://ncbi.nlm.nih.gov/pubmed/27798850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.286484.116 |
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