Identification and molecular characterization of cellular factors required for glucocorticoid receptor-mediated mRNA decay

Glucocorticoid (GC) receptor (GR) has been shown recently to bind a subset of mRNAs and elicit rapid mRNA degradation. However, the molecular details of GR-mediated mRNA decay (GMD) remain unclear. Here, we demonstrate that GMD triggers rapid degradation of target mRNAs in a translation-independent...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Park, Ok Hyun, Park, Joori, Yu, Mira, An, Hyoung-Tae, Ko, Jesang, Kim, Yoon Ki
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066615/
https://ncbi.nlm.nih.gov/pubmed/27798850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.286484.116
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker