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Condensin I-mediated mitotic chromosome assembly requires association with chromokinesin KIF4A

The chromokinesin KIF4A has been implicated in shaping mitotic chromosomes, but its functional relationship to condensin complexes remains controversial. Here, we found that, in mitosis, KIF4A associates with condensin I but not with condensin II. Mutational analyses indicated that the enrichment of...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Takahashi, Motoko, Wakai, Toshifumi, Hirota, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066236/
https://ncbi.nlm.nih.gov/pubmed/27633014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.282855.116
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