Combined Interactions with I(1)-, I(2)-Imidazoline Binding Sites and α(2)-Adrenoceptors To Manage Opioid Addiction

[Image: see text] Tolerance and dependence associated with chronic opioid exposure result from molecular, cellular, and neural network adaptations. Such adaptations concern opioid and nonopioid systems, including α(2)-adrenoceptors (α(2)-ARs) and I(1)- and I(2)-imidazoline binding sites (IBS). Agmat...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Med Chem Lett
Egile Nagusiak: Giusepponi, Maria Elena, Cifani, Carlo, Micioni Di Bonaventura, Maria Vittoria, Mattioli, Laura, Hudson, Alan, Diamanti, Eleonora, Del Bello, Fabio, Giannella, Mario, Mammoli, Valerio, Paoletti, Corinne Dalila, Piergentili, Alessandro, Pigini, Maria, Quaglia, Wilma
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2016
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066154/
https://ncbi.nlm.nih.gov/pubmed/27774136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00290
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