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The promise of epigenomic therapeutics in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is often viewed to arise primarily by genetic alterations. However, today we know that many aspects of the cancer phenotype require a crosstalk among these genetic alterations with epigenetic changes. Indeed, aberrant gene expression patterns, driven by epigen...

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Detalhes bibliográficos
Publicado no:Epigenomics
Main Authors: Lomberk, Gwen A, Iovanna, Juan, Urrutia, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066125/
https://ncbi.nlm.nih.gov/pubmed/27337224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2015-0016
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