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The promise of epigenomic therapeutics in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is often viewed to arise primarily by genetic alterations. However, today we know that many aspects of the cancer phenotype require a crosstalk among these genetic alterations with epigenetic changes. Indeed, aberrant gene expression patterns, driven by epigen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Epigenomics
Hauptverfasser: Lomberk, Gwen A, Iovanna, Juan, Urrutia, Raul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066125/
https://ncbi.nlm.nih.gov/pubmed/27337224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2015-0016
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