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The promise of epigenomic therapeutics in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is often viewed to arise primarily by genetic alterations. However, today we know that many aspects of the cancer phenotype require a crosstalk among these genetic alterations with epigenetic changes. Indeed, aberrant gene expression patterns, driven by epigen...

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Bibliografske podrobnosti
izdano v:Epigenomics
Main Authors: Lomberk, Gwen A, Iovanna, Juan, Urrutia, Raul
Format: Artigo
Jezik:Inglês
Izdano: Future Medicine Ltd 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066125/
https://ncbi.nlm.nih.gov/pubmed/27337224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2015-0016
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