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Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer
Diacylglycerol kinases (DGKs) are a family of enzymes that catalyze the metabolism of diacylglycerol (DAG). Two isoforms of DGK, DGKα, and DGKζ, specifically regulate the pool of DAG that is generated as a second messenger after stimulation of the T cell receptor (TCR). Deletion of either isoform in...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Front Cell Dev Biol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065962/ https://ncbi.nlm.nih.gov/pubmed/27800476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00108 |
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