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Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer
Diacylglycerol kinases (DGKs) are a family of enzymes that catalyze the metabolism of diacylglycerol (DAG). Two isoforms of DGK, DGKα, and DGKζ, specifically regulate the pool of DAG that is generated as a second messenger after stimulation of the T cell receptor (TCR). Deletion of either isoform in...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065962/ https://ncbi.nlm.nih.gov/pubmed/27800476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2016.00108 |
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