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Cellular proteostasis: degradation of misfolded proteins by lysosomes

Proteostasis refers to the regulation of the cellular concentration, folding, interactions and localization of each of the proteins that comprise the proteome. One essential element of proteostasis is the disposal of misfolded proteins by the cellular pathways of protein degradation. Lysosomes are a...

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Bibliografiske detaljer
Udgivet i:Essays Biochem
Main Authors: Jackson, Matthew P., Hewitt, Eric W.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Limited 2016
Fag:
46
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065703/
https://ncbi.nlm.nih.gov/pubmed/27744333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20160005
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