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Are Interactions between cis-Regulatory Variants Evidence for Biological Epistasis or Statistical Artifacts?

The importance of epistasis—or statistical interactions between genetic variants—to the development of complex disease in humans has been controversial. Genome-wide association studies of statistical interactions influencing human traits have recently become computationally feasible and have identif...

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Bibliografski detalji
Izdano u:Am J Hum Genet
Glavni autori: Fish, Alexandra E., Capra, John A., Bush, William S.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065654/
https://ncbi.nlm.nih.gov/pubmed/27640306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.07.022
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