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Are Interactions between cis-Regulatory Variants Evidence for Biological Epistasis or Statistical Artifacts?
The importance of epistasis—or statistical interactions between genetic variants—to the development of complex disease in humans has been controversial. Genome-wide association studies of statistical interactions influencing human traits have recently become computationally feasible and have identif...
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| Veröffentlicht in: | Am J Hum Genet |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5065654/ https://ncbi.nlm.nih.gov/pubmed/27640306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.07.022 |
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