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MULTIVARIATE ANALYSIS OF REGULATORY SNPS: EMPOWERING PERSONAL GENOMICS BY CONSIDERING CIS-EPISTASIS AND HETEROGENEITY

Understanding how genetic variants impact the regulation and expression of genes is important for forging mechanistic links between variants and phenotypes in personal genomics studies. In this work, we investigate statistical interactions among variants that alter gene expression and identify 79 ge...

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Autors principals: TURNER, STEPHEN D., BUSH, WILLIAM S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159159/
https://ncbi.nlm.nih.gov/pubmed/21121055
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