Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

Precise connection of thalamic barreloids with their corresponding cortical barrels is critical for processing of vibrissal sensory information. Here, we show that PRG-2, a phospholipid-interacting molecule, is important for thalamocortical axon guidance. Developing thalamocortical fibers both in PR...

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Published in:Neuron
Main Authors: Cheng, Jin, Sahani, Sadhna, Hausrat, Torben Johann, Yang, Jenq-Wei, Ji, Haichao, Schmarowski, Nikolai, Endle, Heiko, Liu, Xinfeng, Li, Yunbo, Böttche, Rahel, Radyushkin, Konstantin, Maric, Hans M., Hoerder-Suabedissen, Anna, Molnár, Zoltán, Prouvot, Pierre-Hugues, Trimbuch, Thorsten, Ninnemann, Olaf, Huai, Jisen, Fan, Wei, Visentin, Barbara, Sabbadini, Roger, Strømgaard, Kristian, Stroh, Albrecht, Luhmann, Heiko J., Kneussel, Matthias, Nitsch, Robert, Vogt, Johannes
Format: Artigo
Language:Inglês
Published: Cell Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065528/
https://ncbi.nlm.nih.gov/pubmed/27641493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.08.035
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