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Effect of an Ala81His Mutation on the Met80 Loop Dynamics of Iso-1-Cytochrome c()

An A81H variant of yeast iso-1-cytochrome c is prepared to test the hypothesis that the steric size of the amino acid at sequence position 81 of cytochrome c, which has evolved from Ala in yeast to Ile in mammals, slows the dynamics of the opening of the heme crevice. The A81H mutation is used both...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Bandi, Swati, Bowler, Bruce E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065065/
https://ncbi.nlm.nih.gov/pubmed/25671560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501252z
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