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The Response of Ω-Loop D Dynamics to Truncation of Trimethyllysine 72 of Yeast Iso-1-cytochrome c Depends on the Nature of Loop Deformation

Trimethyllysine 72 (tmK72) has been suggested to play a role in sterically constraining the heme crevice dynamics of yeast iso-1-cytochrome c mediated by the Ω-loop D cooperative substructure (residues 70 to 85). A tmK72A mutation causes a gain in peroxidase activity, a function of cytochrome c that...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: McClelland, Levi J., Seagraves, Sean M., Khan, Khurshid Alam, Cherney, Melisa M., Bandi, Swati, Culbertson, Justin E., Bowler, Bruce E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485566/
https://ncbi.nlm.nih.gov/pubmed/25948392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-015-1267-1
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