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Mutagenesis of histidine 26 demonstrates the importance of loop-loop and loop-protein interactions for the function of iso-1-cytochrome c.

In yeast iso-1-cytochrome c, the side chain of histidine 26 (His26) attaches omega loop A to the main body of the protein by forming a hydrogen bond to the backbone atom carbonyl of glutamic acid 44. The His26 side chain also forms a stabilizing intra-loop interaction through a hydrogen bond to the...

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Detalhes bibliográficos
Main Authors: Fetrow, J. S., Dreher, U., Wiland, D. J., Schaak, D. L., Boose, T. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143970/
https://ncbi.nlm.nih.gov/pubmed/9568906
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