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Role of Calpain in Pathogenesis of Human Disease Processes

Calpains are a 15-member class of calcium activated nonlysosomal neutral proteases which are involved in a broad range of cellular function. Calpains are usually localized to the cytosol and within mitochondria. Calpastatin is an endogenous protein that specifically binds to and inhibits calpain. Ov...

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Bibliographic Details
Published in:J Nat Sci
Main Authors: Potz, Brittany A., Abid, M. Ruhul, Sellke, Frank W.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065022/
https://ncbi.nlm.nih.gov/pubmed/27747292
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