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PKCε-mediates resistin-induced NADPH oxidase activation and inflammation leading to smooth muscle cell dysfunction and intimal hyperplasia

BACKGRUND AND AIMS: Resistin has been implicated in cardiovascular disease and poor interventional cardiovascular outcomes. Previous studies by our group demonstrated resistin promoted vascular smooth muscle cell (VSMC) migration through protein kinase C epsilon (PKCε) pathways, while few others sho...

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Détails bibliographiques
Publié dans:Atherosclerosis
Auteurs principaux: Raghuraman, Gayatri, Zuniga, Mary C., Yuan, Hai, Zhou, Wei
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064855/
https://ncbi.nlm.nih.gov/pubmed/27573736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2016.08.015
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