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Hypoxia activates NADPH oxidase to increase [ROS](i) and [Ca(2+)](i) through mitochondrial ROS–PKCε signaling axis in pulmonary artery smooth muscle cells

The importance of NADPH oxidase (Nox) in hypoxic responses in hypoxia-sensing cells including pulmonary artery smooth muscle cells (PASMCs) remains uncertain. In this study, using Western blot analysis we found that the major Nox subunits Nox1, Nox4, p22(phox), p47(phox), and p67(phox) were equivale...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Rathore, Rakesh, Zheng, Yun-Min, Niu, Chun-Feng, Liu, Qing-Hua, Korde, Amit, Ho, Ye-Shih, Wang, Yong-Xiao
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586914/
https://ncbi.nlm.nih.gov/pubmed/18638544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.06.012
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