Hypoxia activates NADPH oxidase to increase [ROS](i) and [Ca(2+)](i) through mitochondrial ROS–PKCε signaling axis in pulmonary artery smooth muscle cells

The importance of NADPH oxidase (Nox) in hypoxic responses in hypoxia-sensing cells including pulmonary artery smooth muscle cells (PASMCs) remains uncertain. In this study, using Western blot analysis we found that the major Nox subunits Nox1, Nox4, p22(phox), p47(phox), and p67(phox) were equivale...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rathore, Rakesh, Zheng, Yun-Min, Niu, Chun-Feng, Liu, Qing-Hua, Korde, Amit, Ho, Ye-Shih, Wang, Yong-Xiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586914/
https://ncbi.nlm.nih.gov/pubmed/18638544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.06.012
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