Mitochondrial ROS-PKCɛ signaling axis is uniquely involved in hypoxic increase in [Ca(2+)](i) in pulmonary artery smooth muscle cells

The molecular mechanisms underlying hypoxic responses in pulmonary and systemic arteries remain obscure. Here we for the first time report that acute hypoxia significantly increased total PKC and PKCɛ activity in pulmonary, but not mesenteric arteries, while these two tissues showed comparable PKCɛ...

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Hauptverfasser: Rathore, Rakesh, Zheng, Yun-Min, Li, Xiao-Qiang, Wang, Qing-Song, Liu, Qing-Hua, Ginnan, Roman R., Singer, Harold A, Ho, Ye-Shih, Wang, Yong-Xiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764638/
https://ncbi.nlm.nih.gov/pubmed/17087917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.10.116
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