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Role of ROS signaling in differential hypoxic Ca(2+) and contractile responses in pulmonary and systemic vascular smooth muscle cells

Hypoxia causes a large increase in [Ca(2+)](i) and attendant contraction in pulmonary artery smooth muscle cells (PASMCs), but not in systemic artery SMCs. The different responses meet the respective functional needs in these two distinct vascular myocytes; however, the underlying molecular mechanis...

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Autores principales: Wang, Yong-Xiao, Zheng, Yun-Min
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991600/
https://ncbi.nlm.nih.gov/pubmed/20713188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2010.08.008
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