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Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes

Diseases of complex origin have a component of quantitative genetics that contributes to their susceptibility and phenotypic variability. However, after several studies, a major part of the genetic component of complex phenotypes has still not been found, a situation known as “missing heritability”....

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Blanco-Gómez, Adrián, Castillo-Lluva, Sonia, del Mar Sáez-Freire, María, Hontecillas-Prieto, Lourdes, Mao, Jian Hua, Castellanos-Martín, Andrés, Pérez-Losada, Jesus
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064854/
https://ncbi.nlm.nih.gov/pubmed/27241833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600084
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