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Anti-inflammatory effect of dual nociceptin and opioid receptor agonist, BU08070, in experimental colitis in mice

Endogenous opioid and nociceptin systems are widely distributed in the gastrointestinal tract where they seem to play a crucial role in maintaining homeostasis. The aim of our study was to assess whether activation of nociceptin (NOP) and μ-opioid (MOP) receptors by a mixed NOP/MOP receptor agonist,...

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Bibliografiske detaljer
Udgivet i:Eur J Pharmacol
Main Authors: Zielińska, Marta, Ben Haddou, Tanila, Cami-Kobeci, Gerta, Sałaga, Maciej, Jarmuż, Agata, Padysz, Milena, Kordek, Radzisław, Spetea, Mariana, Husbands, Stephen M., Fichna, Jakub
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064847/
https://ncbi.nlm.nih.gov/pubmed/26404500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2015.09.021
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