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The PtdIns3‐phosphatase MTMR3 interacts with mTORC1 and suppresses its activity
Macroautophagy is a major intracellular degradation system. We previously reported that overexpression of phosphatase‐deficient MTMR3, a member of the myotubularin phosphatidylinositol (PI) 3‐phosphatase family, leads to induction of autophagy. In this study, we found that MTMR3 interacted with mTOR...
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| Udgivet i: | FEBS Lett |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5064752/ https://ncbi.nlm.nih.gov/pubmed/26787466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12048 |
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