Nontranscriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis

Forkhead box O (FOXO; DAF-16 in nematodes) transcription factors activate a program of genes that control stress resistance, metabolism, and life span. Given the adverse impact of the stochastic DNA damage on organismal development and aging, we examined the role of FOXO/DAF-16 in UV-induced DNA dam...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Daitoku, Hiroaki, Kaneko, Yuta, Yoshimochi, Kenji, Matsumoto, Kaori, Araoi, Sho, Sakamaki, Jun-ichi, Takahashi, Yuta, Fukamizu, Akiyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064221/
https://ncbi.nlm.nih.gov/pubmed/27550812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00265-16
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