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Nontranscriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis

Forkhead box O (FOXO; DAF-16 in nematodes) transcription factors activate a program of genes that control stress resistance, metabolism, and life span. Given the adverse impact of the stochastic DNA damage on organismal development and aging, we examined the role of FOXO/DAF-16 in UV-induced DNA dam...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Daitoku, Hiroaki, Kaneko, Yuta, Yoshimochi, Kenji, Matsumoto, Kaori, Araoi, Sho, Sakamaki, Jun-ichi, Takahashi, Yuta, Fukamizu, Akiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064221/
https://ncbi.nlm.nih.gov/pubmed/27550812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00265-16
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