Optimal Clinical Doses of Faropenem, Linezolid, and Moxifloxacin in Children With Disseminated Tuberculosis: Goldilocks

Background. When treated with the same antibiotic dose, children achieve different 0- to 24-hour area under the concentration-time curves (AUC(0–24)) because of maturation and between-child physiological variability on drug clearance. Children are also infected by Mycobacterium tuberculosis isolates...

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Dettagli Bibliografici
Pubblicato in:Clin Infect Dis
Autori principali: Srivastava, Shashikant, Deshpande, Devyani, Pasipanodya, Jotam, Nuermberger, Eric, Swaminathan, Soumya, Gumbo, Tawanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
A Development Paradigm for Novel Combination Regimens for Multidrug-Resistant and Drug-Susceptible Tuberculosis in Children: Flame for Work and Play
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064158/
https://ncbi.nlm.nih.gov/pubmed/27742641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw483
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