A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way

Background. The regimen of linezolid and moxifloxacin was found to be efficacious in the hollow fiber system model of pediatric intracellular tuberculosis. However, its kill rate was slower than the standard 3-drug regimen of isoniazid, rifampin, and pyrazinamide. We wanted to examine the effect of...

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Veröffentlicht in:Clin Infect Dis
Hauptverfasser: Deshpande, Devyani, Srivastava, Shashikant, Nuermberger, Eric, Pasipanodya, Jotam G., Swaminathan, Soumya, Gumbo, Tawanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
A Development Paradigm for Novel Combination Regimens for Multidrug-Resistant and Drug-Susceptible Tuberculosis in Children: Flame for Work and Play
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064155/
https://ncbi.nlm.nih.gov/pubmed/27742640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw474
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