Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo

Background. No treatment regimens have been specifically designed for children, in whom tuberculosis is predominantly intracellular. Given their activity as monotherapy and their ability to penetrate many diseased anatomic sites that characterize disseminated tuberculosis, linezolid and moxifloxacin...

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Veröffentlicht in:Clin Infect Dis
Hauptverfasser: Deshpande, Devyani, Srivastava, Shashikant, Nuermberger, Eric, Pasipanodya, Jotam G., Swaminathan, Soumya, Gumbo, Tawanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
A Development Paradigm for Novel Combination Regimens for Multidrug-Resistant and Drug-Susceptible Tuberculosis in Children: Flame for Work and Play
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064154/
https://ncbi.nlm.nih.gov/pubmed/27742639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw473
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